Magnesium orotate is a mineral salt that is normally found in small amounts in all living things. Each molecule of magnesium orotate consists of two molecules of orotic acid in which a single magnesium atom replaces a pair of hydrogen atoms (one from each orotic acid molecule).

Orotate (orotic acid) is a biochemical substance made by all living cells. It is a necessary raw material for making the genetic material: RNA and DNA.

Rosmarinic acid, an antioxidant and antimicrobial found in many plants such as rosemary and oregano, prevents cell damage caused by free radical reactions — reactions that are thought to be involved in inflammation, arthritis and the aging process in general. It also shows promise as a preventative for arterial plaque formation, as an HIV integrase inhibitor, and for treating bronchial asthma,  gingivitis and inflammatory diseases in general.